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An Eight-Step Continuous-Flow Total Synthesis of Vitamin B1 Article

Meifen Jiang, Minjie Liu, Weijian Li, Yingqi Xia, Fener Chen

Engineering 2024, Volume 32, Issue 1,   Pages 230-239 doi: 10.1016/j.eng.2023.01.016

Abstract: This study reports on an integrated eight-step continuous-flow synthesis of vitamin B1 fromThe proposed continuous-flow process is based on advances in chemistry, engineering, and equipment designreactors, mixers, separators, and continuous filters.This eight-step continuous-flow protocol enables technology involving up to six of the key principlesHence, the application of flow technology is of paramount importance for improving security, reducing

Keywords： Vitamin B1     Continuous-flow synthesis     Micro-reactor     Continuous manufacturing    

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Estimation of photolysis half-lives of dyes in a continuous-flow system with the aid of quantitative

Davoud BEIKNEJAD,Mohammad Javad CHAICHI

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 5,   Pages 683-692 doi: 10.1007/s11783-014-0680-y

Abstract: of the model dyes in water solutions and under ultraviolet (UV) radiation were determined by using a continuous-flow

Keywords： dye     photolysis half-life     quantitative structure-property relationship     continuous-flow     stepwise multiple    

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Continuous-Flow Synthesis of the Nucleobase Unit of Remdesivir Article

Yongxing Guo, Minjie Liu, Meifen Jiang, Yuan Tao, Dang Cheng, Fen-Er Chen

Engineering 2023, Volume 21, Issue 2,   Pages 92-100 doi: 10.1016/j.eng.2021.07.029

Abstract: antiviral drug remdesivir, 7-bromopyrrolo[2,1-f][1,2,4]triazin-4-amine, was synthesized through five-step continuousflow.chemistry, 7-bromopyrrolo[2,1-f][1,2,4]triazin-4-amine was successfully produced through sequential flowThe salient feature of this synthesis is that the workup procedures are fully integrated into the reactionsequences by deploying dedicated equipment and separation units, thus forming a streamlined continuous-flow

Keywords： Flow chemistry     Continuous multistep synthesis     Microreaction technology     Reaction–separation integration    

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Experimental and theoretical study of microwave enhanced catalytic hydrodesulfurization of thiophene in a continuous-flow

Hui Shang, Pengfei Ye, Yude Yue, Tianye Wang, Wenhui Zhang, Sainab Omar, Jiawei Wang

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 4,   Pages 744-758 doi: 10.1007/s11705-019-1839-7

Abstract: of thiophene, as a gasoline model oil, over an industrial Ni-Mo/Al O catalyst was investigated in a continuous

Keywords： thiophene     microwave irradiation     hydrodesulfurization     non-thermal microwave effect    

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Automated synthesis of steady-state continuous processes using reinforcement learning

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 2,   Pages 288-302 doi: 10.1007/s11705-021-2055-9

Abstract: Automated flowsheet synthesis is an important field in computer-aided process engineering.The present work demonstrates how reinforcement learning can be used for automated flowsheet synthesisTherein, flowsheet synthesis is modelled as a game of two competing players.

Keywords： automated process synthesis     flowsheet synthesis     artificial intelligence     machine learning     reinforcement    

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Cultivation of aerobic granular sludge in a conventional, continuous flow, completely mixed activated

Xi CHEN,Linjiang YUAN,Wenjuan LU,Yuyou LI,Pei LIU,Kun NIE

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 2,   Pages 324-333 doi: 10.1007/s11783-014-0627-3

Abstract: Aerobic granules were formed in a conventional, continuous flow, completely mixed activated sludge system

Keywords： aerobic granular sludge     completely mixed activated sludge system (CMAS)     continuous flow     shear force     filamentous    

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Flow synthesis of a novel zirconium-based UiO-66 nanofiltration membrane and its performance in the removal

Feichao Wu, Yanling Wang, Xiongfu Zhang

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 4,   Pages 651-660 doi: 10.1007/s11705-019-1819-y

Abstract: a thin zirconium-based UiO-66 membrane was successfully prepared on an alumina hollow fiber tube by flowsynthesis, and was used in an attempt to remove -nitrophenol from water through a nanofiltration processTwo main factors, including flow rate and synthesis time, were investigated to optimize the conditionsUnder optimal synthesis conditions, a thin UiO-66 membrane of approximately 2 µm in thickness was fabricatedat a flow rate of 4 mL·h for 30 h.

Keywords： UiO-66 membrane     flow synthesis     nanofiltration     p-nitrophenol removal    

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Continuous flow removal of acid fuchsine by dielectric barrier discharge plasma water bed enhanced by

Rusen Zhou, Renwu Zhou, Xianhui Zhang, Kateryna Bazaka, Kostya (Ken) Ostrikov

Frontiers of Chemical Science and Engineering 2019, Volume 13, Issue 2,   Pages 340-349 doi: 10.1007/s11705-019-1798-z

Abstract: Continuous processes which allow for large amount of wastewater to be treated to meet drainage standardsThe study offers a new opportunity for continuous effective remediation of wastewater contaminated with

Keywords： continuous removal     dye-containing wastewater     dielectric barrier discharge     plasma water bed     activated    

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Hydrogen production from co-gasification of coal and biomass in supercritical water by continuous flow

YAN Qiuhui, GUO Liejin, LIANG Xing, ZHANG Ximin

Frontiers in Energy 2007, Volume 1, Issue 3,   Pages 327-330 doi: 10.1007/s11708-007-0048-0

Abstract: Hydrogen is a clean energy carrier. Converting abundant coal sources and green biomass energy into hydrogen effectively and without any pollution promotes environmental protection. The co-gasification performance of coal and a model compound of biomass, carboxymethylcellulose (CMC) in supercritical water (SCW), were investigated experimentally. The influences of temperature, pressure and concentration on hydrogen production from co-gasification of coal and CMC in SCW under the given conditions (20–25 MPa, 650vH, 15–30 s) are discussed in detail. The experimental results show that H, CO and CH are the main gas products, and the molar fraction of hydrogen reaches in excess of 60%. The higher pressure and higher CMC content facilitate hydrogen production; production is decreased remarkably given a longer residence time.

Keywords： carboxymethylcellulose     temperature     co-gasification performance     Hydrogen     residence    

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Continuous deacylation of amides in a high-temperature and high-pressure microreactor

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 12,   Pages 1818-1825 doi: 10.1007/s11705-022-2182-y

Abstract: To intensify this reaction, a high-temperature and high-pressure continuous microreaction technology

Keywords： amide deacylation     microreactor     flow chemistry     reaction intensification    

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Response of bioaerosol cells to photocatalytic inactivation with ZnO and TiO impregnated onto Perlite and Poraver carriers

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 3, doi: 10.1007/s11783-020-1335-9

Abstract:

•ZnO/Perlite inactivated 72% of bioaerosols in continuous gas phase.

Keywords： Immobilized catalysts     Continuous flow     Photocatalysis     Bioaerosols     Cytotoxicity     Inactivation mechanism    

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Synthesis of poly(maleic acid alkylamide-

Jingjing XU, Jun XU, Jie SUN, Shili XING, Li LI, Xuhong GUO

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 1,   Pages 74-78 doi: 10.1007/s11705-010-0542-5

Abstract: To improve the flow ability of crude oil with high content of aromatic asphaltenes, new comb-type copolymersThe effect of copolymers on the flow ability of model waxy oil and crude oil were studied by rheological

Keywords： comb-polymers     styrene     paraffin     crystallization     flow ability    

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Self-sacrificial templating synthesis of flower-like nickel phyllosilicates and its application as high-performance

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 4,   Pages 484-497 doi: 10.1007/s11705-021-2074-6

Abstract: The nanocomposites of flower-like nickel phyllosilicate particles incorporated into epoxy resin were fabricated via an in-situ mixing process. The flower-like nickel phyllosilicate particles were firstly synthesized using a mild self-sacrificial templating method, and the morphology and lamellar structure were examined carefully. Several properties of mechanical, thermal and tribological responses of epoxy nanocomposites were performed. It was demonstrated that adequate flower-like nickel phyllosilicate particles dispersed well in the matrix, and the nanocomposites displayed enhanced tensile strength and elastic modulus but decreased elongation at break as expected. In addition, friction coefficient and wear rate were increased first and then decreased along with the particle content, and showed the lowest values at a mass fraction of 5%. Nevertheless, the incorporated flower-like nickel phyllosilicate particles resulted in the continuously increasing thermal stability of epoxy resin (EP) nanocomposites. This study revealed the giant potential of flower-like particles in preparing high-quality EP nanocomposites.

Keywords： nickel phyllosilicate     flow-like structure     mechanical property     thermal stability     tribological performance    

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Strain and process engineering toward continuous industrial fermentation

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 10,   Pages 1336-1353 doi: 10.1007/s11705-022-2284-6

Abstract: To increase the economic competitiveness of biological processes, continuous fermentation technologiesHowever, several key challenges should be addressed for the industrial application of continuous fermentation

Keywords： continuous fermentation     productivity     contamination     strain degeneration     metabolic engineering    

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Ant colony optimization in continuous problem

YU Ling, LIU Kang, LI Kaishi

Frontiers of Mechanical Engineering 2007, Volume 2, Issue 4,   Pages 459-462 doi: 10.1007/s11465-007-0079-6

Abstract: Based on the analysis of the basic ant colony optimization and optimum problem in a continuous space,an ant colony optimization (ACO) for continuous problem is constructed and discussed.The algorithm is efficient and beneficial to the study of the ant colony optimization in a continuous

Keywords： beneficial     algorithm     efficient     continuous     ACO    

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Title Author Date Type Operation

An Eight-Step Continuous-Flow Total Synthesis of Vitamin B1

Meifen Jiang, Minjie Liu, Weijian Li, Yingqi Xia, Fener Chen

Journal Article

Estimation of photolysis half-lives of dyes in a continuous-flow system with the aid of quantitative

Davoud BEIKNEJAD,Mohammad Javad CHAICHI

Journal Article

Continuous-Flow Synthesis of the Nucleobase Unit of Remdesivir

Yongxing Guo, Minjie Liu, Meifen Jiang, Yuan Tao, Dang Cheng, Fen-Er Chen

Journal Article

Experimental and theoretical study of microwave enhanced catalytic hydrodesulfurization of thiophene in a continuous-flow

Hui Shang, Pengfei Ye, Yude Yue, Tianye Wang, Wenhui Zhang, Sainab Omar, Jiawei Wang

Journal Article

Automated synthesis of steady-state continuous processes using reinforcement learning

Journal Article

Cultivation of aerobic granular sludge in a conventional, continuous flow, completely mixed activated

Xi CHEN,Linjiang YUAN,Wenjuan LU,Yuyou LI,Pei LIU,Kun NIE

Journal Article

Flow synthesis of a novel zirconium-based UiO-66 nanofiltration membrane and its performance in the removal

Feichao Wu, Yanling Wang, Xiongfu Zhang

Journal Article

Continuous flow removal of acid fuchsine by dielectric barrier discharge plasma water bed enhanced by

Rusen Zhou, Renwu Zhou, Xianhui Zhang, Kateryna Bazaka, Kostya (Ken) Ostrikov

Journal Article

Hydrogen production from co-gasification of coal and biomass in supercritical water by continuous flow

YAN Qiuhui, GUO Liejin, LIANG Xing, ZHANG Ximin

Journal Article

Continuous deacylation of amides in a high-temperature and high-pressure microreactor

Journal Article

Response of bioaerosol cells to photocatalytic inactivation with ZnO and TiO impregnated onto Perlite and Poraver carriers

Journal Article

Synthesis of poly(maleic acid alkylamide-

Jingjing XU, Jun XU, Jie SUN, Shili XING, Li LI, Xuhong GUO

Journal Article

Self-sacrificial templating synthesis of flower-like nickel phyllosilicates and its application as high-performance

Journal Article

Strain and process engineering toward continuous industrial fermentation

Journal Article

Ant colony optimization in continuous problem

YU Ling, LIU Kang, LI Kaishi

Journal Article